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Monday, 12 September
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08:30 – 10:30 |
Session 9b: Virus-Host Interactions
Session Chairs: Kui Li and Ming Loo |
Grand Ballroom CD |
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08:30 |
A RIG-I translocon directs membrane-association of RIG-I with IPS-1 and controls innate antiviral immunity
Helene Minyi Liu, Michael Gale Jr. |
O9.09 |
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08:45 |
Unraveling the complexity of the type I interferon antiviral response
John Schoggins, Sam Wilson, Maryline Panis, Mary Murphy, Christoper Jones, Paul Bieniasz, Charles Rice |
O9.10 |
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09:00 |
In vivo suppression of interferon sensitive gene 15 (ISG15), a proviral host factor in HCV replication, enhances the endogenous interferon response
Catherine I. Real, Ruth Broering, Kerstin Jahn-Hofmann, Ludger Ickenstein, Matthias John, Kathrin Kleinehr, Guido Gerken, Joerg F. Schlaak |
O9.11 |
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09:15 |
Robust induction of type III interferons and other cytokines defines a unique pattern of innate immunity in response to hepatitis C virus infection
Emmanuel Thomas, Veronica Gonzalez, Qisheng Li, Ankit Modi, Weiping Chen, Mazen Noureddin, Yaron Rotman, T. Jake Liang |
O9.12 |
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09:30 |
Systems biology & computational network analysis identifies mitochondrial host targets of HCV infection and liver disease progression
Deborah L. Diamond, Jason E. McDermott, Alexei Krasnoselsky, Kristin E. Burnum, Nathan Susnow, Bobbie-Jo Webb-Robertson, Courtney Courley, Matthew M. Yeh, Angela L. Rasmussen, Jon M. Jacobs, Renuka Bhattacharya, James D. Perkins, Robert L. Carithers Jr., Marina A. Gritsenko, Iris W. Liou, Susan Strom, Katrina M. Waters, Richard D. Smith, Michael G. Katze |
O9.13 |
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09:45 |
Overall structural model of non-structural protein 5A from hepatitis C virus and modulation by cyclophilin A
Aurelie Badillo, Veronique Receveur-Brechot, Simona Miron, Xavier Hanoulle, Jennifer Molle, Roland Montserret, Ralf Bartenschlager, Guy Lippens, Sylvie Ricard-Blum, Francois Penin |
O9.14 |
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10:00 |
Hepatitis C virus infection induces autophagy and blocks innate immune response
Shubham Shrivastava, Amit Raychoudhuri, Robert Steele, Ranjit Ray, Ratna Ray |
O9.15 |
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10:15 |
Differential type I interferon-mediated autophagic trafficking of hepatitis C virus proteins in mouse liver
Mayura Desai, Bin Gong, Tehsheng Chan, Jiaren Sun |
O9.16 |
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10:30 – 11:00 |
Refreshment Break |
Grand Ballroom Pre-Function Area |
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11:00 – 12:30 |
Session 10: Viral Kinetics and Drug Resistance
Session Chairs: John D. Scott and Evaldo Stanislau |
Grand Ballroom CD |
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11:00 |
Project ECHO: outcomes of hepatitis C treatment by primary care providers
Sanjeev Arora, Karla Thornton, Summers Kalishman, Paulina Deming, Wesley Pak, John Brown, Glen Murata |
O10.01 |
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11:15 |
Molecular characterization of HCV resistance to telaprevir by means of ultra-deep pyrosqequencing
Stephane Chevaliez, Christophe Rodriguez, Alexandre Soulier, Abdelhakim Ahmed-Belkacem, Christophe Hezode, Jean-Michel Pawlotsky |
O10.02 |
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11:30 |
New insights into the mechanism of action of interferon-alpha and BMS-790052: a multi-scale mathematical modeling approach
Jeremie Guedj, Harel Dahari, Libin Rong, Richard Nettles, Scott Cotler, Thomas Layden, Alan Perelson |
O10.03 |
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11:45 |
HCV persistence after sustained virological response to antiviral therapy in patients with or without past exposure to hepatitis B virus Tram N. Q. Pham, Carla S. Coffin, Norma D. Churchill, Stefan J. Urbanski, Samuel S. Lee, Thomas I. Michalak |
O10.04 |
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12:00 |
Long-term follow-up of chronic HCV patients treated with telaprevir: evaluation of persistence of resistant variants by ultra-deep sequencing
Xiomara Thomas, Joep de Bruijne, Tara Kieffer, James Sullivan, Sjoerd Rebers, Michel de Vries, Henk Reesink, Christine Weegink, Janke Schinkel, Richard Molenkamp |
O10.05 |
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12:15 |
Selection of cyclophilin inhibitor resistance in transplant patient
Rob Striker, Israr Ansari, Todd Allen, Andrew Berical |
O10.06 |
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12:30 – 13:00 |
Closing Remarks |
Grand Ballroom CD |
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